This search is to detect a suspicious rundll32.exe process having a http connection and do a dns query in some web domain. This technique was seen in IcedID malware where the rundll32 that execute its payload will contact amazon.com to check internet connect and to communicate to its C&C server to download config and other file component.
Rundll32 Dnsquery Help
To successfully implement this search, you need to be ingesting logs with the process name and eventcode = 22 dnsquery executions from your endpoints. If you are using Sysmon, you must have at least version 6.0.4 of the Sysmon TA. Tune and filter known instances where renamed rundll32.exe may be used.
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